MicroSprayer^® Model IA-1C

REFERENCES

Beck, S.E., Laube, B.L., Adams, R., Chesnut, K.A. Flotte, T.R., and Guggino, W.B. (1999) Deposition and distribution of aerosolized AAV vectors in the lungs of macaques. Poster Session, 13th Ann North Am Cystic Fibrosis Conf.

Beck, S.E., Laube, B.L., Adams, R., Chesnut, K.A., Flotte, T.R., and Guggino, W.B. (1999) Deposition of aerosolized AAV vectors in the lungs of Rhesus macaques. Ped Pulm 228:229(Suppl.)19A.

Beck, S.E., Laube, B.L., Adams, R., Chesnut, K.A., Flotte, T.R., and Guggino, W.B. (2000) Deposition of aerosolized AAV vectors in the lungs of Rhesus macaques. Am J Resp Crit Care Med 161:3(2)(Suppl.)A73.

Beck, S.E., Laube, B.L., Barberena, C.I., Fischer, A.C., Adams, R.J., Chesnut, K., Flotte, T.R., and Guggino, W.B. (2002) Deposition and expression of aerosolized rAAV vectors in the lungs of Rhesus macaques. Molecular Therapy 6:546-554.

Century, T..J. (2000) A new intrapulmonary aerosol delivery device. Respiratory Drug Delivery VII, Vol. II, 459, Serentec Press.

Century, T..J. (2000) Efficacy studies of a new intrapulmonary aerosolizer. Poster Session, Respiratory Drug Delivery VII.

Chen, T.-W., Miller, I.F., and Yeates, D.B. (1996) Reversal of transepithelial water transport by dry air and hypertonic saline challenge in canine airways. Presentation, Am Inst of Chemical Engineers Ann Meeting.

Chen, B.T., and Yeates, D.B. (2000) Differentiation of ion-associated and osmotically driven water transport in canine airways. Am J Respir Crit Care Med 162:1715-1722.

Chen, B.T., and Yeates, D.B. (2001) Ion transport and regulation of respiratory tract fluid output in dogs. J Appl Physiol 90:821-831.

Delepine, P., Montier, T., Guillaume, C., Vaysse, L., LePape, A., and Ferec, C. (2002) Visualization of the transgene distribution according to the administration route allows prediction of the transfection efficacy and validation of the results obtained. Gene Therapy 9:736-739.

Fischer, A., Barberena, C.I., Laube, B.L., Beck, S.E., and Guggino, W.B. (2002) Repeated airway administration of rAAV2 results in increased transgene expression. Presentation, Am Soc of Gene Therapy, 5th Annual Meeting, Abstract No. 123.

Flotte, T.R., and Laube, B.L. (2001) Gene therapy in cystic fibrosis. Chest 120:124S-131S.

Schnell, M.A., Raper, S., Century, T., Tazelaar, J. Chirmule, N., Wivel, N., Glover, E., Stephens, L., Baker, C., Wilson, J.M., and Hughes, J.V. (1998) Use of the Penn-Century sprayer device for pulmonary delivery of adenoviral vectors in pre-clinical toxicology studies. Inst for Human Gene Therapy, 6th Ann Retreat.

Schughart, K., Bischoff, R., Rasmussen, U.B., Ali Hadji, D., Perraud, F.,Accart, N., Boussif, O., Silvestre, N., Cordier, Y., Pavirani, A., and Kolbe, H.V.J. (1999) Solvoplex: a new type of synthetic vector for intrapulmonary gene delivery. Human Gene Therapy 10:2891-2905.

Tepper, J., Pfeiffer, J., Aldrich, M., Tumas, D., Kern, J., Hoffman, E., McLennan, G., and Hyde, D. (2000) Can retinoic acid ameliorate the physiologic and morphologic effects of elastase instillation in the rat? Chest 117:242S-244S.